Deletion of a 4977-bp Fragment in the Mitochondrial Genome Is Associated with Mitochondrial Disease Severity

Yanchun Zhang; Yinan Ma; Dingfang Bu; Hui Liu; Changyu Xia; Ying Zhang; Sainan Zhu; Hong Pan; Pei Pei; Xuefei Zheng; Songtao Wang; Yufeng Xu; Yu Qi

doi:10.1371/journal.pone.0128624

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Open Access

Peer-reviewed

Research Article

Deletion of a 4977-bp Fragment in the Mitochondrial Genome Is Associated with Mitochondrial Disease Severity

Yanchun Zhang,

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Yinan Ma ,

* E-mail: mayinan1014@163.com (YM); qiyu0724@163.com (YQ)

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Dingfang Bu,

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Hui Liu,

Affiliation Department of Respiratory, Beijing Children’s Hospital, Beijing, 100045, China
⨯
Changyu Xia,

Affiliation Department of Clinical Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Ying Zhang,

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Sainan Zhu,

Affiliation Department of Biostatistics, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Hong Pan,

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Pei Pei,

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Xuefei Zheng,

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Songtao Wang,

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Yufeng Xu,

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯
Yu Qi

* E-mail: mayinan1014@163.com (YM); qiyu0724@163.com (YQ)

Affiliation Department of Central Laboratory, Peking University First Hospital, No. 8, West District, Beijing, 100034, China
⨯

Deletion of a 4977-bp Fragment in the Mitochondrial Genome Is Associated with Mitochondrial Disease Severity

Yanchun Zhang,
Yinan Ma,
Dingfang Bu,
Hui Liu,
Changyu Xia,
Ying Zhang,
Sainan Zhu,
Hong Pan,
Pei Pei,
Xuefei Zheng

Published: May 29, 2015
https://doi.org/10.1371/journal.pone.0128624

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