Pareto Optimization Identifies Diverse Set of Phosphorylation Signatures Predicting Response to Treatment with Dasatinib

Open Access

Peer-reviewed

Research Article

Martin Klammer,

Affiliation Evotec (München) GmbH, Dept. of Bioinformatics, Am Klopferspitz 19a, 82152 Martinsried, Germany
⨯
J. Nikolaj Dybowski,

Affiliation Evotec (München) GmbH, Dept. of Bioinformatics, Am Klopferspitz 19a, 82152 Martinsried, Germany
⨯
Daniel Hoffmann,

Affiliation Center for Medical Biotechnology, University of Duisburg-Essen, Universitätsstrasse 1-4, 45141 Essen, Germany
⨯
Christoph Schaab

* E-mail: christoph.schaab@evotec.com

Affiliations Evotec (München) GmbH, Dept. of Bioinformatics, Am Klopferspitz 19a, 82152 Martinsried, Germany, Max-Plack Institute for Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany
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Phosphorylation
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Breast cancer
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Protein interaction networks
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Support vector machines
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Optimization
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