Structural Studies of the HIV-1 Integrase Protein: Compound Screening and Characterization of a DNA-Binding Inhibitor

Open Access

Peer-reviewed

Research Article

Peter K. Quashie ,

Contributed equally to this work with: Peter K. Quashie, Ying-Shan Han

Affiliations McGill University AIDS Centre, Lady Davis for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada, Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
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Ying-Shan Han ,

Contributed equally to this work with: Peter K. Quashie, Ying-Shan Han

Affiliation McGill University AIDS Centre, Lady Davis for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada
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Said Hassounah,

Affiliations McGill University AIDS Centre, Lady Davis for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada, Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
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Thibault Mesplède,

Affiliation McGill University AIDS Centre, Lady Davis for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada
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Mark A. Wainberg

* E-mail: mark.wainberg@mcgill.ca

Affiliations McGill University AIDS Centre, Lady Davis for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada, Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, Quebec, Canada, Department of Microbiology and Immunology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
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HIV
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Crystal structure
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HIV-1
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Sequence alignment
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DNA structure
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Protein structure comparison
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Dimers
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Monomers
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