Increased Missense Mutation Burden of Fatty Acid Metabolism Related Genes in Nunavik Inuit Population

Sirui Zhou; Lan Xiong; Pingxing Xie; Amirthagowri Ambalavanan; Cynthia V. Bourassa; Alexandre Dionne-Laporte; Dan Spiegelman; Maude Turcotte Gauthier; Edouard Henrion; Ousmane Diallo; Patrick A. Dion; Guy A. Rouleau

doi:10.1371/journal.pone.0128255

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Open Access

Peer-reviewed

Research Article

Increased Missense Mutation Burden of Fatty Acid Metabolism Related Genes in Nunavik Inuit Population

Sirui Zhou,

Affiliations Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada, Département de médecine, Faculté de médecine, Université de Montréal, Montréal (Que), Canada
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Lan Xiong,

Affiliations Département de psychiatrie, Faculté de médecine, Université de Montréal, Montréal (Que), Canada, Centre de recherche, Institut universitaire en santé mentale de Montréal (Que), Canada
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Pingxing Xie,

Affiliations Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada, Department of Human Genetics, McGill University, Montréal (Que), Canada
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Amirthagowri Ambalavanan,

Affiliations Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada, Department of Human Genetics, McGill University, Montréal (Que), Canada
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Cynthia V. Bourassa,

Affiliation Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada
⨯
Alexandre Dionne-Laporte,

Affiliation Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada
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Dan Spiegelman,

Affiliation Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada
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Maude Turcotte Gauthier,

Affiliation Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada
⨯
Edouard Henrion,

Affiliation Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada
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Ousmane Diallo,

Affiliation Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada
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Patrick A. Dion,

Affiliations Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada, Department of Neurology and Neurosurgery, McGill University, Montréal (Que), Canada
⨯
Guy A. Rouleau

* E-mail: guy.rouleau@mcgill.ca

Affiliations Montreal Neurological Institute and Hospital, McGill University, Montréal (Que), Canada, Department of Neurology and Neurosurgery, McGill University, Montréal (Que), Canada
⨯

Increased Missense Mutation Burden of Fatty Acid Metabolism Related Genes in Nunavik Inuit Population

Sirui Zhou,
Lan Xiong,
Pingxing Xie,
Amirthagowri Ambalavanan,
Cynthia V. Bourassa,
Alexandre Dionne-Laporte,
Dan Spiegelman,
Maude Turcotte Gauthier,
Edouard Henrion,
Ousmane Diallo

Published: May 26, 2015
https://doi.org/10.1371/journal.pone.0128255

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Single nucleotide polymorphisms
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