The EGFR/ErbB3 Pathway Acts as a Compensatory Survival Mechanism upon c-Met Inhibition in Human c-Met+ Hepatocellular Carcinoma

Open Access

Peer-reviewed

Research Article

The EGFR/ErbB3 Pathway Acts as a Compensatory Survival Mechanism upon c-Met Inhibition in Human c-Met⁺ Hepatocellular Carcinoma

Steven N. Steinway,

Affiliation Department of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Hien Dang,

Current address: Laboratory of Human Carcinogenesis Branch, Liver Carcinogenesis Section, National Cancer Institute, Bethesda, Maryland, United States of America

Affiliation Department of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Hanning You,

Current address: Department of Medicine, The Pennsylvania State University, College of Medicine, Pennsylvania, United States of America

Affiliation Department of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯
C. Bart Rountree,

Current address: Bon Secours Pediatric Gastroenterology Associates, Richmond, Virginia, United States of America

Affiliation Department of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Wei Ding

* E-mail: wding@hmc.psu.edu

Affiliation Department of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America
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Hepatocellular carcinoma
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EGFR signaling
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Small interfering RNA
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Lung and intrathoracic tumors
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Transfection
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Cell viability testing
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Cancer treatment
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Metastasis
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