Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure

Luisa A. Baker; Karla C. L. Lee; Carolina Palacios Jimenez; Hatim Alibhai; Yu-Mei Chang; Pamela J. Leckie; Rajeshwar P. Mookerjee; Nathan A. Davies; Fausto Andreola; Rajiv Jalan

doi:10.1371/journal.pone.0128076

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Peer-reviewed

Research Article

Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure

Luisa A. Baker,

Affiliation Department of Clinical Science and Services, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
⨯
Karla C. L. Lee,

Affiliation Department of Clinical Science and Services, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
⨯
Carolina Palacios Jimenez,

Affiliation Department of Clinical Science and Services, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
⨯
Hatim Alibhai,

Affiliation Department of Clinical Science and Services, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
⨯
Yu-Mei Chang,

Affiliation Department of Clinical Science and Services, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
⨯
Pamela J. Leckie,

Affiliation Liver Failure Group, University College London Institute for Liver and Digestive Health, University College London Medical School, Royal Free Hospital, London, United Kingdom
⨯
Rajeshwar P. Mookerjee,

Affiliation Liver Failure Group, University College London Institute for Liver and Digestive Health, University College London Medical School, Royal Free Hospital, London, United Kingdom
⨯
Nathan A. Davies,

Affiliation Liver Failure Group, University College London Institute for Liver and Digestive Health, University College London Medical School, Royal Free Hospital, London, United Kingdom
⨯
Fausto Andreola ,

¶‡ These authors are joint senior authors on this work.

Affiliation Liver Failure Group, University College London Institute for Liver and Digestive Health, University College London Medical School, Royal Free Hospital, London, United Kingdom
⨯
Rajiv Jalan

* E-mail: r.jalan@ucl.ac.uk

¶‡ These authors are joint senior authors on this work.

Affiliation Liver Failure Group, University College London Institute for Liver and Digestive Health, University College London Medical School, Royal Free Hospital, London, United Kingdom
⨯

Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure

Luisa A. Baker,
Karla C. L. Lee,
Carolina Palacios Jimenez,
Hatim Alibhai,
Yu-Mei Chang,
Pamela J. Leckie,
Rajeshwar P. Mookerjee,
Nathan A. Davies,
Fausto Andreola,
Rajiv Jalan

Published: May 27, 2015
https://doi.org/10.1371/journal.pone.0128076

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