Autophagy-Regulated ROS from Xanthine Oxidase Acts as an Early Effector for Triggering Late Mitochondria-Dependent Apoptosis in Cathepsin S-Targeted Tumor Cells

• Chien-Chang Huang,

  Affiliation National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, ROC

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• Cheng-Che Lee,

  Affiliation National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, ROC

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• Hsiao-Han Lin,

  Affiliations National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, ROC, The Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC

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• Mei-Chi Chen,

  Affiliation National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, ROC

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• Chun-Cheng Lin,

  Affiliation Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan, ROC

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• Jang-Yang Chang

  * E-mail: jychang@nhri.org.tw

  Affiliations National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, ROC, Division of Hematology and Oncology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC, Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC

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