Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APCMin/+ Mice

Joshua S. Son; Shanawaj Khair; Donald W. Pettet III; Nengtai Ouyang; Xinyu Tian; Yuanhao Zhang; Wei Zhu; Gerardo G. Mackenzie; Charles E. Robertson; Diana Ir; Daniel N. Frank; Basil Rigas; Ellen Li

doi:10.1371/journal.pone.0127985

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Open Access

Peer-reviewed

Research Article

Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APC^Min/+ Mice

Joshua S. Son,

Affiliation Department of Medicine, Stony Brook University, Stony Brook, NY, United States of America
⨯
Shanawaj Khair,

Affiliation Department of Medicine, Stony Brook University, Stony Brook, NY, United States of America
⨯
Donald W. Pettet III,

Affiliation Department of Medicine, Stony Brook University, Stony Brook, NY, United States of America
⨯
Nengtai Ouyang,

Affiliation Department of Medicine, Stony Brook University, Stony Brook, NY, United States of America
⨯
Xinyu Tian,

Affiliation Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, United States of America
⨯
Yuanhao Zhang,

Affiliation Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, United States of America
⨯
Wei Zhu,

Affiliation Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, United States of America
⨯
Gerardo G. Mackenzie,

Affiliation Department of Preventive Medicine, Stony Brook University, Stony Brook, NY, United States of America
⨯
Charles E. Robertson,

Affiliation Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
⨯
Diana Ir,

Affiliation Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
⨯
Daniel N. Frank,

Affiliation Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
⨯
Basil Rigas,

Affiliation Department of Medicine, Stony Brook University, Stony Brook, NY, United States of America
⨯
Ellen Li

* E-mail: ellen.li@stonybrookmedicine.edu

Affiliation Department of Medicine, Stony Brook University, Stony Brook, NY, United States of America
⨯

Altered Interactions between the Gut Microbiome and Colonic Mucosa Precede Polyposis in APC^Min/+ Mice

Joshua S. Son,
Shanawaj Khair,
Donald W. Pettet III,
Nengtai Ouyang,
Xinyu Tian,
Yuanhao Zhang,
Wei Zhu,
Gerardo G. Mackenzie,
Charles E. Robertson,
Diana Ir

Published: June 29, 2015
https://doi.org/10.1371/journal.pone.0127985

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