A Model for Aryl Hydrocarbon Receptor-Activated Gene Expression Shows Potency and Efficacy Changes and Predicts Squelching Due to Competition for Transcription Co-Activators

Open Access

Peer-reviewed

Research Article

Ted W. Simon ,

* E-mail: ted@tedsimon-toxicology.com

Affiliation Ted Simon LLC, Winston, GA, United States of America
⨯
Robert A. Budinsky,

Affiliation The Dow Chemical Company, Toxicology and Environmental Research & Consulting. Midland, MI, United States of America
⨯
J. Craig Rowlands

Affiliation The Dow Chemical Company, Toxicology and Environmental Research & Consulting. Midland, MI, United States of America
⨯

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DNA transcription
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Gene expression
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Transcription factors
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Messenger RNA
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Cell binding assay
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RNA polymerase
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DNA-binding proteins
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Hydrocarbons
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