Physiologically Based Pharmacokinetic Modeling Is Essential in 90Y-Labeled Anti-CD66 Radioimmunotherapy

Open Access

Peer-reviewed

Research Article

Physiologically Based Pharmacokinetic Modeling Is Essential in ⁹⁰Y-Labeled Anti-CD66 Radioimmunotherapy

Peter Kletting ,

Contributed equally to this work with: Peter Kletting, Christian Maaß

Affiliation Department of Nuclear Medicine, Ulm University, 89070, Ulm, Germany
⨯
Christian Maaß ,

Contributed equally to this work with: Peter Kletting, Christian Maaß

* E-mail: christian.maass@medma.uni-heidelberg.de

Affiliation Medical Radiation Physics/Radiation Protection, Medical Faculty Mannheim, Heidelberg University, 68167, Mannheim, Germany
⨯
Sven Reske,

Affiliation Department of Nuclear Medicine, Ulm University, 89070, Ulm, Germany
⨯
Ambros J. Beer,

Affiliation Department of Nuclear Medicine, Ulm University, 89070, Ulm, Germany
⨯
Gerhard Glatting

Affiliation Medical Radiation Physics/Radiation Protection, Medical Faculty Mannheim, Heidelberg University, 68167, Mannheim, Germany
⨯

Antibody therapy
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Spleen
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Radiolabeling
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Radioimmunotherapy
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Liver
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Curve fitting
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Cancer treatment
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