High-Throughput Assay Development for Cystine-Glutamate Antiporter (x_c^-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells

• Ajit G. Thomas,

  Affiliation Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America

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• Rita Sattler,

  Affiliations Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America

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• Karen Tendyke,

  Affiliation Next Generation Systems CFU, Eisai Inc., Andover, MA, 01810, United States of America

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• Kara A. Loiacono,

  Affiliation Next Generation Systems CFU, Eisai Inc., Andover, MA, 01810, United States of America

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• Hans Hansen,

  Affiliation Next Generation Systems CFU, Eisai Inc., Andover, MA, 01810, United States of America

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• Vishal Sahni,

  Affiliation Neuroscience and General Medicine PCU, Eisai Inc., Andover, MA, 01810, United States of America

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• Yutaka Hashizume,

  Affiliation Neuroscience and General Medicine PCU, Eisai Inc., Andover, MA, 01810, United States of America

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• Camilo Rojas ,

  * E-mail: crojas2@jhmi.edu (CR); bslusher@jhmi.edu (BSS)

  Affiliations Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America, Department of Comparative Medicine and Molecular Pathobiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America

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• Barbara S. Slusher

  * E-mail: crojas2@jhmi.edu (CR); bslusher@jhmi.edu (BSS)

  Affiliations Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America, Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America, Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, United States of America

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