Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity

Jenny Dworzak; Benoît Renvoisé; Johnny Habchi; Emma V. Yates; Christophe Combadière; Tuomas P. Knowles; Christopher M. Dobson; Craig Blackstone; Ole Paulsen; Philip M. Murphy

doi:10.1371/journal.pone.0127730

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Open Access

Peer-reviewed

Research Article

Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity

Jenny Dworzak,

Affiliations Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, United States of America, Neuronal Oscillations Group, Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, United Kingdom, Cell Biology Section, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
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Benoît Renvoisé,

Affiliation Cell Biology Section, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
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Johnny Habchi,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
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Emma V. Yates,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
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Christophe Combadière,

Affiliation Centre d'Immunologie et des Maladies Infectieuses-Paris, Institut National de la Santé et de la Recherche Médicale, Paris, France
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Tuomas P. Knowles,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
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Christopher M. Dobson,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
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Craig Blackstone,

Affiliation Cell Biology Section, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
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Ole Paulsen ,

* E-mail: pmm@nih.gov (PMM); op210@cam.ac.uk (OP)

Affiliation Neuronal Oscillations Group, Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, United Kingdom
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Philip M. Murphy

* E-mail: pmm@nih.gov (PMM); op210@cam.ac.uk (OP)

Affiliation Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity

Jenny Dworzak,
Benoît Renvoisé,
Johnny Habchi,
Emma V. Yates,
Christophe Combadière,
Tuomas P. Knowles,
Christopher M. Dobson,
Craig Blackstone,
Ole Paulsen,
Philip M. Murphy

Published: June 3, 2015
https://doi.org/10.1371/journal.pone.0127730

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