Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy

Open Access

Peer-reviewed

Research Article

Wooseong Kim,

Affiliation Division of Infectious Diseases, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯
Annie L. Conery,

Affiliation Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Rajmohan Rajamuthiah,

Affiliations Division of Infectious Diseases, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Beth Burgwyn Fuchs,

Affiliations Division of Infectious Diseases, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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Frederick M. Ausubel,

Affiliation Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Eleftherios Mylonakis

* E-mail: emylonakis@lifespan.org

Affiliation Division of Infectious Diseases, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, Rhode Island, United States of America
⨯

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Methicillin-resistant Staphylococcus aureus
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Antibiotics
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Bacterial biofilms
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Cell membranes
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Staphylococcus aureus
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Vancomycin
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Membrane characteristics
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Antibiotic resistance
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