A Central Role for JNK/AP-1 Pathway in the Pro-Oxidant Effect of Pyrrolidine Dithiocarbamate through Superoxide Dismutase 1 Gene Repression and Reactive Oxygen Species Generation in Hematopoietic Human Cancer Cell Line U937

Open Access

Peer-reviewed

Research Article

Humberto Riera ,

Contributed equally to this work with: Humberto Riera, Valéry Afonso

Affiliation Unidad de Reumatología, Nivel plaza del Instituto Autónomo Hospital Universitario de Los Andes. Mérida, Venezuela
⨯
Valéry Afonso ,

Contributed equally to this work with: Humberto Riera, Valéry Afonso

Affiliation INSERM U1029, Laboratoire de l'Angiogenèse et du Microenvironnement des Cancers, Pessac, France
⨯
Pascal Collin,

Affiliation UMR 8601, Laboratoire de Chimie & Biochimie Pharmacologique, Paris, France
⨯
Abderrahim Lomri

* E-mail: rahim.lomri@inserm.fr

Affiliation INSERM U1029, Laboratoire de l'Angiogenèse et du Microenvironnement des Cancers, Pessac, France
⨯

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c-Jun N-terminal kinase signaling cascade
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Breast cancer
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Reactive oxygen species
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Messenger RNA
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