The Dilemma of Heterogeneity Tests in Meta-Analysis: A Challenge from a Simulation Study

Shi-jun Li; Hua Jiang; Hao Yang; Wei Chen; Jin Peng; Ming-wei Sun; Charles Damien Lu; Xi Peng; Jun Zeng

doi:10.1371/journal.pone.0127538

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Open Access

Peer-reviewed

Research Article

The Dilemma of Heterogeneity Tests in Meta-Analysis: A Challenge from a Simulation Study

Shi-jun Li ,

Contributed equally to this work with: Shi-jun Li, Hua Jiang, Hao Yang, Wei Chen, Jun Zeng

Affiliation Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People’s Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China
⨯
Hua Jiang ,

Contributed equally to this work with: Shi-jun Li, Hua Jiang, Hao Yang, Wei Chen, Jun Zeng

* E-mail: cdjianghua@gmail.com

Affiliations Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People’s Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China, Department of Parenteral and Enteral Nutrition, Peking Union Medical College Hospital, Beijing, China, Institute of Burn Research, Southwest Hospital of the Third Military Medical University, Chongqing, China
⨯
Hao Yang ,

Contributed equally to this work with: Shi-jun Li, Hua Jiang, Hao Yang, Wei Chen, Jun Zeng

Affiliation Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People’s Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China
⨯
Wei Chen ,

Contributed equally to this work with: Shi-jun Li, Hua Jiang, Hao Yang, Wei Chen, Jun Zeng

Affiliations Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People’s Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China, Department of Parenteral and Enteral Nutrition, Peking Union Medical College Hospital, Beijing, China
⨯
Jin Peng,

Affiliation Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People’s Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China
⨯
Ming-wei Sun,

Affiliation Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People’s Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China
⨯
Charles Damien Lu,

Affiliation Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People’s Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China
⨯
Xi Peng,

Affiliations Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People’s Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China, Institute of Burn Research, Southwest Hospital of the Third Military Medical University, Chongqing, China
⨯
Jun Zeng

Contributed equally to this work with: Shi-jun Li, Hua Jiang, Hao Yang, Wei Chen, Jun Zeng

Affiliation Department of Computational Mathematics and Bio-statistics, Metabolomics and Multidisciplinary Laboratory for Trauma Research, Sichuan Provincial People’s Hospital, Sichuan Academy of Medical Sciences, Chengdu, Sichuan, China
⨯

The Dilemma of Heterogeneity Tests in Meta-Analysis: A Challenge from a Simulation Study

Shi-jun Li,
Hua Jiang,
Hao Yang,
Wei Chen,
Jin Peng,
Ming-wei Sun,
Charles Damien Lu,
Xi Peng,
Jun Zeng

Published: May 29, 2015
https://doi.org/10.1371/journal.pone.0127538

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