TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation

Xinxin Ci; Masayuki Kuraoka; Hongxia Wang; Zachary Carico; Kristen Hopper; Jinwook Shin; Xuming Deng; Yirong Qiu; Shyam Unniraman; Garnett Kelsoe; Xiao-Ping Zhong

doi:10.1371/journal.pone.0127527

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Open Access

Peer-reviewed

Research Article

TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation

Xinxin Ci ,

Contributed equally to this work with: Xinxin Ci, Masayuki Kuraoka

Affiliations Department of Pediatrics, Duke University Medical Center, Durham, NC, 27710, United States of America, Key Laboratory of Zoonosis Ministry of Education, Institute of Zoonosis, College of Animal Science and Veterinary Medicine, Jilin University, Changchun, 130062, China
⨯
Masayuki Kuraoka ,

Contributed equally to this work with: Xinxin Ci, Masayuki Kuraoka

Affiliation Department of Immunology, Duke University Medical Center, Durham, NC, 27710, United States of America
⨯
Hongxia Wang,

Affiliations Department of Pediatrics, Duke University Medical Center, Durham, NC, 27710, United States of America, Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China
⨯
Zachary Carico,

Affiliation Department of Immunology, Duke University Medical Center, Durham, NC, 27710, United States of America
⨯
Kristen Hopper,

Affiliation Department of Immunology, Duke University Medical Center, Durham, NC, 27710, United States of America
⨯
Jinwook Shin,

Affiliation Department of Pediatrics, Duke University Medical Center, Durham, NC, 27710, United States of America
⨯
Xuming Deng,

Affiliation Key Laboratory of Zoonosis Ministry of Education, Institute of Zoonosis, College of Animal Science and Veterinary Medicine, Jilin University, Changchun, 130062, China
⨯
Yirong Qiu,

Affiliation Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China
⨯
Shyam Unniraman,

Affiliation Department of Immunology, Duke University Medical Center, Durham, NC, 27710, United States of America
⨯
Garnett Kelsoe ,

* E-mail: zhong001@mc.duke.edu (XPZ); ghkelsoe@duke.edu (GK)

Affiliation Department of Immunology, Duke University Medical Center, Durham, NC, 27710, United States of America
⨯
Xiao-Ping Zhong

* E-mail: zhong001@mc.duke.edu (XPZ); ghkelsoe@duke.edu (GK)

Affiliations Department of Pediatrics, Duke University Medical Center, Durham, NC, 27710, United States of America, Department of Immunology, Duke University Medical Center, Durham, NC, 27710, United States of America
⨯

TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation

Xinxin Ci,
Masayuki Kuraoka,
Hongxia Wang,
Zachary Carico,
Kristen Hopper,
Jinwook Shin,
Xuming Deng,
Yirong Qiu,
Shyam Unniraman,
Garnett Kelsoe

Published: May 22, 2015
https://doi.org/10.1371/journal.pone.0127527

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