Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats

P. L. M. Dalpiaz; A. Z. Lamas; I. F. Caliman; E. H. Ribeiro; G. R. Abreu; M. R. Moyses; T. U. Andrade; S. A. Gouvea; M. F. Alves; A. K. Carmona; N. S. Bissoli

doi:10.1371/journal.pone.0127515

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Peer-reviewed

Research Article

Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats

P. L. M. Dalpiaz ,

* E-mail: polyvitoria@yahoo.com.br

Affiliation Department of Physiological Sciences, Federal University of Espirito Santo, Vitória, Espirito Santo, Brazil
⨯
A. Z. Lamas,

Affiliation Department of Physiological Sciences, Federal University of Espirito Santo, Vitória, Espirito Santo, Brazil
⨯
I. F. Caliman,

Affiliation Department of Physiological Sciences, Federal University of Espirito Santo, Vitória, Espirito Santo, Brazil
⨯
E. H. Ribeiro,

Affiliation Department of Physiological Sciences, Federal University of Espirito Santo, Vitória, Espirito Santo, Brazil
⨯
G. R. Abreu,

Affiliation Department of Physiological Sciences, Federal University of Espirito Santo, Vitória, Espirito Santo, Brazil
⨯
M. R. Moyses,

Affiliation Department of Physiological Sciences, Federal University of Espirito Santo, Vitória, Espirito Santo, Brazil
⨯
T. U. Andrade,

Affiliation Department of Pharmacy, University Vila Velha, Vila Velha, Espirito Santo, Brazil
⨯
S. A. Gouvea,

Affiliation Nucleus of Biotechnology, Federal University of Espirito Santo, Vitória, Espirito Santo, Brazil
⨯
M. F. Alves,

Affiliation Department of Biophysics, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, Brazil
⨯
A. K. Carmona,

Affiliation Department of Biophysics, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, Brazil
⨯
N. S. Bissoli

Affiliation Department of Physiological Sciences, Federal University of Espirito Santo, Vitória, Espirito Santo, Brazil
⨯

Sex Hormones Promote Opposite Effects on ACE and ACE2 Activity, Hypertrophy and Cardiac Contractility in Spontaneously Hypertensive Rats

P. L. M. Dalpiaz,
A. Z. Lamas,
I. F. Caliman,
E. H. Ribeiro,
G. R. Abreu,
M. R. Moyses,
T. U. Andrade,
S. A. Gouvea,
M. F. Alves,
A. K. Carmona

Published: May 26, 2015
https://doi.org/10.1371/journal.pone.0127515

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