Ambient Fine Particulate Matter Suppresses In Vivo Proliferation of Bone Marrow Stem Cells through Reactive Oxygen Species Formation

Yuqi Cui; Fengpeng Jia; Jianfeng He; Xiaoyun Xie; Zhihong Li; Minghuan Fu; Hong Hao; Ying Liu; Dylan Z. Liu; Peter J. Cowan; Hua Zhu; Qinghua Sun; Zhenguo Liu

doi:10.1371/journal.pone.0127309

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Open Access

Peer-reviewed

Research Article

Ambient Fine Particulate Matter Suppresses In Vivo Proliferation of Bone Marrow Stem Cells through Reactive Oxygen Species Formation

Yuqi Cui,

Affiliations Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America, Department of Cardiology, Shandong Provincial Hospital, Shandong University, 324 Jing 5 road, Jinan, Shandong 250021, P.R. China
⨯
Fengpeng Jia,

Affiliations Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America, Department of Cardiovascular Medicine, the First Affiliated Hospital,Chongqing Medical University, Chongqing 400016, China
⨯
Jianfeng He,

Affiliation Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America
⨯
Xiaoyun Xie,

Affiliation Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America
⨯
Zhihong Li,

Affiliation Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America
⨯
Minghuan Fu,

Affiliation Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America
⨯
Hong Hao,

Affiliation Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America
⨯
Ying Liu,

Affiliation Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America
⨯
Dylan Z. Liu,

Affiliation Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America
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Peter J. Cowan,

Affiliation Department of Medicine, University of Melbourne, St. Vincent’s Hospital, Melbourne, Australia
⨯
Hua Zhu,

Affiliations Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America, Department of Surgery, Wexner Medical Center, The Ohio State University, Columbus, OH, United States of America
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Qinghua Sun,

Affiliation Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America
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Zhenguo Liu

* E-mail: zhenguo.liu@osumc.edu

Affiliation Dorothy M. Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, The Ohio State University, Columbus, OH, United States of America
⨯

Ambient Fine Particulate Matter Suppresses In Vivo Proliferation of Bone Marrow Stem Cells through Reactive Oxygen Species Formation

Yuqi Cui,
Fengpeng Jia,
Jianfeng He,
Xiaoyun Xie,
Zhihong Li,
Minghuan Fu,
Hong Hao,
Ying Liu,
Dylan Z. Liu,
Peter J. Cowan

Published: June 9, 2015
https://doi.org/10.1371/journal.pone.0127309

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