LZ-207, a Newly Synthesized Flavonoid, Induces Apoptosis and Suppresses Inflammation-Related Colon Cancer by Inhibiting the NF-κB Signaling Pathway

Jie Sun; Fanni Li; Yue Zhao; Li Zhao; Chen Qiao; Zhiyu Li; Qinglong Guo; Na Lu

doi:10.1371/journal.pone.0127282

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Research Article

LZ-207, a Newly Synthesized Flavonoid, Induces Apoptosis and Suppresses Inflammation-Related Colon Cancer by Inhibiting the NF-κB Signaling Pathway

Jie Sun,

Affiliation State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China
⨯
Fanni Li,

Affiliation State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China
⨯
Yue Zhao,

Affiliation State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China
⨯
Li Zhao,

Affiliation State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China
⨯
Chen Qiao,

Affiliation State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China
⨯
Zhiyu Li,

Affiliation School of Pharmacy, China Pharmaceutical University, Nanjing 210009, People’s Republic of China
⨯
Qinglong Guo ,

* E-mail: anticancer_drug@163.com (QG); luna555@163.com (NL)

Affiliation State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China
⨯
Na Lu

* E-mail: anticancer_drug@163.com (QG); luna555@163.com (NL)

Affiliation State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China
⨯

LZ-207, a Newly Synthesized Flavonoid, Induces Apoptosis and Suppresses Inflammation-Related Colon Cancer by Inhibiting the NF-κB Signaling Pathway

Jie Sun,
Fanni Li,
Yue Zhao,
Li Zhao,
Chen Qiao,
Zhiyu Li,
Qinglong Guo,
Na Lu

Published: May 29, 2015
https://doi.org/10.1371/journal.pone.0127282

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