Natural Killer Cells Promote Long-Term Hepatobiliary Inflammation in a Low-Dose Rotavirus Model of Experimental Biliary Atresia

James E. Squires; Pranavkumar Shivakumar; Reena Mourya; Kazuhiko Bessho; Stephanie Walters; Jorge A. Bezerra

doi:10.1371/journal.pone.0127191

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Peer-reviewed

Research Article

Natural Killer Cells Promote Long-Term Hepatobiliary Inflammation in a Low-Dose Rotavirus Model of Experimental Biliary Atresia

James E. Squires,

Affiliation Department of Pediatrics of the University of Cincinnati College of Medicine, the Division of Gastroenterology, Hepatology and Nutrition and the Pediatric Liver Care Center of Cincinnati Children’s Hospital Medical Center; Cincinnati, Ohio, United States of America
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Pranavkumar Shivakumar,

Affiliation Department of Pediatrics of the University of Cincinnati College of Medicine, the Division of Gastroenterology, Hepatology and Nutrition and the Pediatric Liver Care Center of Cincinnati Children’s Hospital Medical Center; Cincinnati, Ohio, United States of America
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Reena Mourya,

Affiliation Department of Pediatrics of the University of Cincinnati College of Medicine, the Division of Gastroenterology, Hepatology and Nutrition and the Pediatric Liver Care Center of Cincinnati Children’s Hospital Medical Center; Cincinnati, Ohio, United States of America
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Kazuhiko Bessho,

Affiliation Division of Pediatrics, Osaka University, Osaka, Japan
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Stephanie Walters,

Affiliation Department of Pediatrics of the University of Cincinnati College of Medicine, the Division of Gastroenterology, Hepatology and Nutrition and the Pediatric Liver Care Center of Cincinnati Children’s Hospital Medical Center; Cincinnati, Ohio, United States of America
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Jorge A. Bezerra

* E-mail: jorge.bezerra@cchmc.org

Affiliation Department of Pediatrics of the University of Cincinnati College of Medicine, the Division of Gastroenterology, Hepatology and Nutrition and the Pediatric Liver Care Center of Cincinnati Children’s Hospital Medical Center; Cincinnati, Ohio, United States of America
⨯

Natural Killer Cells Promote Long-Term Hepatobiliary Inflammation in a Low-Dose Rotavirus Model of Experimental Biliary Atresia

James E. Squires,
Pranavkumar Shivakumar,
Reena Mourya,
Kazuhiko Bessho,
Stephanie Walters,
Jorge A. Bezerra

Published: May 19, 2015
https://doi.org/10.1371/journal.pone.0127191

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NK cells
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Bile ducts
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Gene expression
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