Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors

Patrick N. Harter; Lukas Jennewein; Peter Baumgarten; Elena Ilina; Michael C. Burger; Anna-Luisa Thiepold; Julia Tichy; Martin Zörnig; Christian Senft; Joachim P. Steinbach; Michel Mittelbronn; Michael W. Ronellenfitsch

doi:10.1371/journal.pone.0127123

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Open Access

Peer-reviewed

Research Article

Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors

Patrick N. Harter ,

* E-mail: patrick.harter@kgu.de (PNH); m.ronellenfitsch@gmx.net (MWR)

Affiliations Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Frankfurt am Main, Germany, German Cancer Consortium (DKTK), Heidelberg, Germany, German Cancer Research Center (DKFZ), Heidelberg, Germany
⨯
Lukas Jennewein,

Affiliation Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Frankfurt am Main, Germany
⨯
Peter Baumgarten,

Affiliations Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Frankfurt am Main, Germany, Department of Neurosurgery, University of Frankfurt am Main, Frankfurt am Main, Germany
⨯
Elena Ilina,

Affiliation Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Frankfurt am Main, Germany
⨯
Michael C. Burger,

Affiliations German Cancer Consortium (DKTK), Heidelberg, Germany, German Cancer Research Center (DKFZ), Heidelberg, Germany, Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany
⨯
Anna-Luisa Thiepold,

Affiliation Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany
⨯
Julia Tichy,

Affiliation Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany
⨯
Martin Zörnig,

Affiliation Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany
⨯
Christian Senft,

Affiliations German Cancer Consortium (DKTK), Heidelberg, Germany, German Cancer Research Center (DKFZ), Heidelberg, Germany, Department of Neurosurgery, University of Frankfurt am Main, Frankfurt am Main, Germany
⨯
Joachim P. Steinbach,

Affiliations German Cancer Consortium (DKTK), Heidelberg, Germany, German Cancer Research Center (DKFZ), Heidelberg, Germany, Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany
⨯
Michel Mittelbronn,

Affiliations Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Frankfurt am Main, Germany, German Cancer Consortium (DKTK), Heidelberg, Germany, German Cancer Research Center (DKFZ), Heidelberg, Germany
⨯
Michael W. Ronellenfitsch

* E-mail: patrick.harter@kgu.de (PNH); m.ronellenfitsch@gmx.net (MWR)

Affiliations German Cancer Consortium (DKTK), Heidelberg, Germany, German Cancer Research Center (DKFZ), Heidelberg, Germany, Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany
⨯

Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors

Patrick N. Harter,
Lukas Jennewein,
Peter Baumgarten,
Elena Ilina,
Michael C. Burger,
Anna-Luisa Thiepold,
Julia Tichy,
Martin Zörnig,
Christian Senft,
Joachim P. Steinbach

Published: May 19, 2015
https://doi.org/10.1371/journal.pone.0127123

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Glioma
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Immunohistochemistry techniques
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