The MS Risk Allele of CD40 Is Associated with Reduced Cell-Membrane Bound Expression in Antigen Presenting Cells: Implications for Gene Function

• Judith Field ,

  * E-mail: judith.field@florey.edu.au

  Affiliation Multiple Sclerosis Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria., Australia

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• Fernando Shahijanian,

  Affiliation Centre for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales, Australia

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• Stephen Schibeci,

  Affiliation Centre for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales, Australia

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• Australia and New Zealand MS Genetics Consortium (ANZgene) ,

  ¶Membership of the ANZgene Consortium appears in the Acknowledgments.

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• Laura Johnson,

  Affiliation Multiple Sclerosis Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria., Australia

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• Melissa Gresle,

  Affiliations Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia, Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia

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• Louise Laverick,

  Affiliations Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia, Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia

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• Grant Parnell,

  Affiliation Centre for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales, Australia

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• Graeme Stewart,

  Affiliation Centre for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales, Australia

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• Fiona McKay,

  Affiliation Centre for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales, Australia

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• Trevor Kilpatrick,

  Affiliations Multiple Sclerosis Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria., Australia, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia, Melbourne Neuroscience Institute, University of Melbourne, Melbourne, Victoria, Australia

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• Helmut Butzkueven,

  Affiliations Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia, Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia

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• David Booth

  Affiliation Centre for Immunology and Allergy Research, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales, Australia

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