Reduced Bacterial Colony Count of Anaerobic Bacteria Is Associated with a Worsening in Lung Clearance Index and Inflammation in Cystic Fibrosis

Katherine O’Neill; Judy M. Bradley; Elinor Johnston; Stephanie McGrath; Leanne McIlreavey; Stephen Rowan; Alastair Reid; Ian Bradbury; Gisli Einarsson; J. Stuart Elborn; Michael M. Tunney

doi:10.1371/journal.pone.0126980

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Peer-reviewed

Research Article

Reduced Bacterial Colony Count of Anaerobic Bacteria Is Associated with a Worsening in Lung Clearance Index and Inflammation in Cystic Fibrosis

Katherine O’Neill ,

Contributed equally to this work with: Katherine O’Neill, J. Stuart Elborn, Michael M. Tunney

* E-mail: k.oneill@qub.ac.uk

Affiliations CF and Airways Microbiology Research Group, Queen’s University Belfast, Belfast, United Kingdom, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom
⨯
Judy M. Bradley,

Affiliation Centre for Health and Rehabilitation Technologies (CHART), University of Ulster, Belfast, United Kingdom
⨯
Elinor Johnston,

Affiliations CF and Airways Microbiology Research Group, Queen’s University Belfast, Belfast, United Kingdom, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom
⨯
Stephanie McGrath,

Affiliations CF and Airways Microbiology Research Group, Queen’s University Belfast, Belfast, United Kingdom, School of Pharmacy, Queen’s University Belfast, Belfast, United Kingdom
⨯
Leanne McIlreavey,

Affiliations CF and Airways Microbiology Research Group, Queen’s University Belfast, Belfast, United Kingdom, School of Pharmacy, Queen’s University Belfast, Belfast, United Kingdom
⨯
Stephen Rowan,

Affiliations CF and Airways Microbiology Research Group, Queen’s University Belfast, Belfast, United Kingdom, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom
⨯
Alastair Reid,

Affiliation Belfast Health and Social Care Trust, Belfast, United Kingdom
⨯
Ian Bradbury,

Affiliation Centre for Health and Rehabilitation Technologies (CHART), University of Ulster, Belfast, United Kingdom
⨯
Gisli Einarsson,

Affiliations CF and Airways Microbiology Research Group, Queen’s University Belfast, Belfast, United Kingdom, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom
⨯
J. Stuart Elborn ,

Contributed equally to this work with: Katherine O’Neill, J. Stuart Elborn, Michael M. Tunney

Affiliations CF and Airways Microbiology Research Group, Queen’s University Belfast, Belfast, United Kingdom, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University Belfast, Belfast, United Kingdom
⨯
Michael M. Tunney

Contributed equally to this work with: Katherine O’Neill, J. Stuart Elborn, Michael M. Tunney

Affiliations CF and Airways Microbiology Research Group, Queen’s University Belfast, Belfast, United Kingdom, School of Pharmacy, Queen’s University Belfast, Belfast, United Kingdom
⨯

Reduced Bacterial Colony Count of Anaerobic Bacteria Is Associated with a Worsening in Lung Clearance Index and Inflammation in Cystic Fibrosis

Katherine O’Neill,
Judy M. Bradley,
Elinor Johnston,
Stephanie McGrath,
Leanne McIlreavey,
Stephen Rowan,
Alastair Reid,
Ian Bradbury,
Gisli Einarsson,
J. Stuart Elborn

Published: May 20, 2015
https://doi.org/10.1371/journal.pone.0126980

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