Overexpression of Telomerase Protects Human and Murine Lung Epithelial Cells from Fas- and Bleomycin-Induced Apoptosis via FLIP Upregulation

Nissim Arish; Pazit Y. Cohen; Regina Golan-Gerstl; Zvi Fridlender; Mark Richter Dayan; Philip Zisman; Raphael Breuer; Shulamit B. Wallach-Dayan

doi:10.1371/journal.pone.0126730

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Peer-reviewed

Research Article

Overexpression of Telomerase Protects Human and Murine Lung Epithelial Cells from Fas- and Bleomycin-Induced Apoptosis via FLIP Upregulation

Nissim Arish,

Affiliation Laboratory for Lung Cellular & Molecular Biology, Institute of Pulmonary Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel
⨯
Pazit Y. Cohen,

Affiliation Laboratory for Lung Cellular & Molecular Biology, Institute of Pulmonary Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel
⨯
Regina Golan-Gerstl,

Affiliation Laboratory for Lung Cellular & Molecular Biology, Institute of Pulmonary Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel
⨯
Zvi Fridlender,

Affiliations Laboratory for Lung Cellular & Molecular Biology, Institute of Pulmonary Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel, Department of Pulmonary and Critical Care Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, United States of America
⨯
Mark Richter Dayan,

Affiliation Department of Emergency Medicine, Shaare Zedek Medical Center, Jerusalem, Israel
⨯
Philip Zisman,

Affiliation Laboratory for Lung Cellular & Molecular Biology, Institute of Pulmonary Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel
⨯
Raphael Breuer,

Affiliations Laboratory for Lung Cellular & Molecular Biology, Institute of Pulmonary Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel, Department of Pathology, Boston University School of Medicine, Boston, MA, United States of America
⨯
Shulamit B. Wallach-Dayan

* E-mail: wallach-dayan@hadassah.org.il

Affiliation Laboratory for Lung Cellular & Molecular Biology, Institute of Pulmonary Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel
⨯

Overexpression of Telomerase Protects Human and Murine Lung Epithelial Cells from Fas- and Bleomycin-Induced Apoptosis via FLIP Upregulation

Nissim Arish,
Pazit Y. Cohen,
Regina Golan-Gerstl,
Zvi Fridlender,
Mark Richter Dayan,
Philip Zisman,
Raphael Breuer,
Shulamit B. Wallach-Dayan

Published: May 7, 2015
https://doi.org/10.1371/journal.pone.0126730

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Apoptosis
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Epithelial cells
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Transfection
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Flow cytometry
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Fibrosis
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Lung and intrathoracic tumors
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Secondary lung tumors
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