Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections

Damien Portevin; Félicien Moukambi; Maxmillian Mpina; Asli Bauer; Frederick Haraka; Mkunde Chachage; Philipp Metzger; Elmar Saathoff; Petra Clowes; Nyanda E. Ntinginya; Andrea Rachow; Michael Hoelscher; Klaus Reither; Claudia A. Daubenberger; Christof Geldmacher

doi:10.1371/journal.pone.0126716

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Open Access

Peer-reviewed

Research Article

Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections

Damien Portevin ,

* E-mail: geldmacher@lrz.uni-muenchen.de (CG); damien.portevin@unibas.ch (DP)

Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
⨯
Félicien Moukambi,

Affiliations NIMR-Mbeya Medical Research Centre, Mbeya, Tanzania, Department of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich, Munich, Germany
⨯
Maxmillian Mpina,

Affiliation Ifakara Health Institute, Bagamoyo, Tanzania
⨯
Asli Bauer,

Affiliations NIMR-Mbeya Medical Research Centre, Mbeya, Tanzania, Department of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich, Munich, Germany
⨯
Frederick Haraka,

Affiliation Ifakara Health Institute, Bagamoyo, Tanzania
⨯
Mkunde Chachage,

Affiliation NIMR-Mbeya Medical Research Centre, Mbeya, Tanzania
⨯
Philipp Metzger,

Affiliation Swiss Tropical and Public Health Institute, Basel, Switzerland
⨯
Elmar Saathoff,

Affiliations Department of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich, Munich, Germany, German Centre for Infection Research (DZIF), partner site Munich, Munich, Germany
⨯
Petra Clowes,

Affiliations NIMR-Mbeya Medical Research Centre, Mbeya, Tanzania, Department of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich, Munich, Germany
⨯
Nyanda E. Ntinginya,

Affiliation NIMR-Mbeya Medical Research Centre, Mbeya, Tanzania
⨯
Andrea Rachow,

Affiliations Department of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich, Munich, Germany, German Centre for Infection Research (DZIF), partner site Munich, Munich, Germany
⨯
Michael Hoelscher,

Affiliations Department of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich, Munich, Germany, German Centre for Infection Research (DZIF), partner site Munich, Munich, Germany
⨯
Klaus Reither,

Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland, Ifakara Health Institute, Bagamoyo, Tanzania
⨯
Claudia A. Daubenberger,

Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland
⨯
Christof Geldmacher

* E-mail: geldmacher@lrz.uni-muenchen.de (CG); damien.portevin@unibas.ch (DP)

Affiliations Department of Infectious Diseases and Tropical Medicine, Medical Centre of the University of Munich, Munich, Germany, German Centre for Infection Research (DZIF), partner site Munich, Munich, Germany
⨯

Maturation and Mip-1β Production of Cytomegalovirus-Specific T Cell Responses in Tanzanian Children, Adolescents and Adults: Impact by HIV and Mycobacterium tuberculosis Co-Infections

Damien Portevin,
Félicien Moukambi,
Maxmillian Mpina,
Asli Bauer,
Frederick Haraka,
Mkunde Chachage,
Philipp Metzger,
Elmar Saathoff,
Petra Clowes,
Nyanda E. Ntinginya

Published: May 14, 2015
https://doi.org/10.1371/journal.pone.0126716

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