Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome

Woo-Chang Cheong; Hye-Ri Kang; Hyunyee Yoon; Suk-Jo Kang; Jenny P.-Y. Ting; Moon Jung Song

doi:10.1371/journal.pone.0126456

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Open Access

Peer-reviewed

Research Article

Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome

Woo-Chang Cheong,

Affiliation Virus-Host Interactions Laboratory, Department of Biosystems and Biotechnology, Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 136–713, Republic of Korea
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Hye-Ri Kang,

Affiliation Virus-Host Interactions Laboratory, Department of Biosystems and Biotechnology, Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 136–713, Republic of Korea
⨯
Hyunyee Yoon,

Affiliations Virus-Host Interactions Laboratory, Department of Biosystems and Biotechnology, Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 136–713, Republic of Korea, Laboratory of Protein Immunology, Biomedical Research Institute, Seoul National University Hospital, Seoul, 110–744, Republic of Korea
⨯
Suk-Jo Kang,

Affiliation Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, 305–701, Republic of Korea
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Jenny P.-Y. Ting,

Affiliation Departments of Genetics, Microbiology and Immunology, Center for Translational Immunology and Inflammatory Disease Institute, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, 27599, United States of America
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Moon Jung Song

* E-mail: moonsong@korea.ac.kr

Affiliation Virus-Host Interactions Laboratory, Department of Biosystems and Biotechnology, Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, 136–713, Republic of Korea
⨯

Influenza A Virus NS1 Protein Inhibits the NLRP3 Inflammasome

Woo-Chang Cheong,
Hye-Ri Kang,
Hyunyee Yoon,
Suk-Jo Kang,
Jenny P.-Y. Ting,
Moon Jung Song

Published: May 15, 2015
https://doi.org/10.1371/journal.pone.0126456

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Inflammasomes
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Influenza A virus
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Macrophages
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Immune receptor signaling
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Transcription factors
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Immunoprecipitation
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Cell differentiation
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