Identification of Non-HIV Immunogens That Bind to Germline b12 Predecessors and Prime for Elicitation of Cross-clade Neutralizing HIV-1 Antibodies

Zheng Yang; Jingjing Li; Qingsheng Liu; Tingting Yuan; Yanyu Zhang; Li-Qing Chen; Qi Lou; Zehua Sun; Huazhong Ying; Jianqing Xu; Dimiter S. Dimitrov; Mei-Yun Zhang

doi:10.1371/journal.pone.0126428

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Open Access

Peer-reviewed

Research Article

Identification of Non-HIV Immunogens That Bind to Germline b12 Predecessors and Prime for Elicitation of Cross-clade Neutralizing HIV-1 Antibodies

Zheng Yang,

Affiliation AIDS Institute, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China
⨯
Jingjing Li,

Affiliation AIDS Institute, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China
⨯
Qingsheng Liu,

Affiliation AIDS Institute, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China
⨯
Tingting Yuan,

Affiliation AIDS Institute, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China
⨯
Yanyu Zhang,

Affiliation AIDS Institute, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China
⨯
Li-Qing Chen,

Affiliation Center of Laboratory Animals, Zhejiang Academy of Medical Sciences, Zhejiang, China
⨯
Qi Lou,

Affiliation Center of Laboratory Animals, Zhejiang Academy of Medical Sciences, Zhejiang, China
⨯
Zehua Sun,

Affiliation AIDS Institute, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China
⨯
Huazhong Ying,

Affiliation Center of Laboratory Animals, Zhejiang Academy of Medical Sciences, Zhejiang, China
⨯
Jianqing Xu,

Affiliation Institutes of Biomedical Sciences, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China
⨯
Dimiter S. Dimitrov,

Affiliation Protein Interactions group, Laboratory of Immunology, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America
⨯
Mei-Yun Zhang

* E-mail: zhangmy2014@hotmail.com

Affiliations AIDS Institute, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong, China, Liver Disease Institute, Shenzhen Third People’s Hospital, Shenzhen, 518112, China
⨯

Identification of Non-HIV Immunogens That Bind to Germline b12 Predecessors and Prime for Elicitation of Cross-clade Neutralizing HIV-1 Antibodies

Zheng Yang,
Jingjing Li,
Qingsheng Liu,
Tingting Yuan,
Yanyu Zhang,
Li-Qing Chen,
Qi Lou,
Zehua Sun,
Huazhong Ying,
Jianqing Xu

Published: May 26, 2015
https://doi.org/10.1371/journal.pone.0126428

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