Assembly of a Comprehensive Regulatory Network for the Mammalian Circadian Clock: A Bioinformatics Approach

Robert Lehmann; Liam Childs; Philippe Thomas; Monica Abreu; Luise Fuhr; Hanspeter Herzel; Ulf Leser; Angela Relógio

doi:10.1371/journal.pone.0126283

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Open Access

Peer-reviewed

Research Article

Assembly of a Comprehensive Regulatory Network for the Mammalian Circadian Clock: A Bioinformatics Approach

Robert Lehmann,

Affiliation Institute for Theoretical Biology (ITB), Charité-Universitätsmedizin Berlin and Humboldt-Universität zu Berlin, Invalidenstraße 43, 10115, Berlin, Germany
⨯
Liam Childs ,

Contributed equally to this work with: Liam Childs, Philippe Thomas

Affiliation Knowledge Management in Bioinformatics, Institute for Computer Science, Humboldt-Universität zu Berlin, Unter den Linden 6, 10099, Berlin, Germany
⨯
Philippe Thomas ,

Contributed equally to this work with: Liam Childs, Philippe Thomas

Affiliation Knowledge Management in Bioinformatics, Institute for Computer Science, Humboldt-Universität zu Berlin, Unter den Linden 6, 10099, Berlin, Germany
⨯
Monica Abreu,

Affiliations Institute for Theoretical Biology (ITB), Charité-Universitätsmedizin Berlin and Humboldt-Universität zu Berlin, Invalidenstraße 43, 10115, Berlin, Germany, Molekulares Krebsforschungszentrum (MKFZ), Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
⨯
Luise Fuhr,

Affiliations Institute for Theoretical Biology (ITB), Charité-Universitätsmedizin Berlin and Humboldt-Universität zu Berlin, Invalidenstraße 43, 10115, Berlin, Germany, Molekulares Krebsforschungszentrum (MKFZ), Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
⨯
Hanspeter Herzel,

Affiliation Institute for Theoretical Biology (ITB), Charité-Universitätsmedizin Berlin and Humboldt-Universität zu Berlin, Invalidenstraße 43, 10115, Berlin, Germany
⨯
Ulf Leser,

Affiliation Knowledge Management in Bioinformatics, Institute for Computer Science, Humboldt-Universität zu Berlin, Unter den Linden 6, 10099, Berlin, Germany
⨯
Angela Relógio

* E-mail: angela.relogio@charite.de

Affiliations Institute for Theoretical Biology (ITB), Charité-Universitätsmedizin Berlin and Humboldt-Universität zu Berlin, Invalidenstraße 43, 10115, Berlin, Germany, Molekulares Krebsforschungszentrum (MKFZ), Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
⨯

Assembly of a Comprehensive Regulatory Network for the Mammalian Circadian Clock: A Bioinformatics Approach

Robert Lehmann,
Liam Childs,
Philippe Thomas,
Monica Abreu,
Luise Fuhr,
Hanspeter Herzel,
Ulf Leser,
Angela Relógio

Published: May 6, 2015
https://doi.org/10.1371/journal.pone.0126283

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Circadian oscillators
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Gene regulation
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Circadian rhythms
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