Small Heat Shock Protein Beta-1 (HSPB1) Is Upregulated and Regulates Autophagy and Apoptosis of Renal Tubular Cells in Acute Kidney Injury

Tatsuki Matsumoto; Madoka Urushido; Haruna Ide; Masayuki Ishihara; Kazu Hamada-Ode; Yoshiko Shimamura; Koji Ogata; Kosuke Inoue; Yoshinori Taniguchi; Takafumi Taguchi; Taro Horino; Shimpei Fujimoto; Yoshio Terada

doi:10.1371/journal.pone.0126229

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Open Access

Peer-reviewed

Research Article

Small Heat Shock Protein Beta-1 (HSPB1) Is Upregulated and Regulates Autophagy and Apoptosis of Renal Tubular Cells in Acute Kidney Injury

Tatsuki Matsumoto,

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯
Madoka Urushido,

Affiliation Center for Innovative and Translational Medicine, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan
⨯
Haruna Ide,

Affiliation Center for Innovative and Translational Medicine, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan
⨯
Masayuki Ishihara,

Affiliation Department of Pediatrics, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Japan
⨯
Kazu Hamada-Ode,

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯
Yoshiko Shimamura,

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯
Koji Ogata,

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯
Kosuke Inoue,

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯
Yoshinori Taniguchi,

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯
Takafumi Taguchi,

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯
Taro Horino,

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯
Shimpei Fujimoto,

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯
Yoshio Terada

* E-mail: terada@kochi-u.ac.jp

Affiliation Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University Kohasu, Oko-cho, Nankoku, Japan
⨯

Small Heat Shock Protein Beta-1 (HSPB1) Is Upregulated and Regulates Autophagy and Apoptosis of Renal Tubular Cells in Acute Kidney Injury

Tatsuki Matsumoto,
Madoka Urushido,
Haruna Ide,
Masayuki Ishihara,
Kazu Hamada-Ode,
Yoshiko Shimamura,
Koji Ogata,
Kosuke Inoue,
Yoshinori Taniguchi,
Takafumi Taguchi

Published: May 11, 2015
https://doi.org/10.1371/journal.pone.0126229

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Autophagic cell death
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Apoptosis
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Transfection
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Kidneys
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Small interfering RNA
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Protein expression
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Heat shock response
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