Caenorhabditis elegans as a Model System for Studying Drug Induced Mitochondrial Toxicity

Richard de Boer; Ruben L. Smith; Winnok H. De Vos; Erik M. M. Manders; Stanley Brul; Hans van der Spek

doi:10.1371/journal.pone.0126220

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Peer-reviewed

Research Article

Caenorhabditis elegans as a Model System for Studying Drug Induced Mitochondrial Toxicity

Richard de Boer ,

Contributed equally to this work with: Richard de Boer, Ruben L. Smith

Affiliation Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands
⨯
Ruben L. Smith ,

Contributed equally to this work with: Richard de Boer, Ruben L. Smith

Affiliation Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands
⨯
Winnok H. De Vos,

Affiliations Cell Biology and Histology Group, Department of Veterinary Sciences, University of Antwerp, Groenenborgerlaan 171, 2020, Antwerp, Belgium, Cell Systems and Imaging Research Group, Department of Molecular Biotechnology, Ghent University, Coupure Links, 653, 9000, Ghent, Belgium
⨯
Erik M. M. Manders,

Affiliation van Leeuwenhoek Center for Advanced Microscopy, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands
⨯
Stanley Brul,

Affiliation Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands
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Hans van der Spek

* E-mail: j.c.vanderspek@uva.nl

Affiliation Molecular Biology & Microbial Food Safety, Swammerdam Institute for Life Sciences (SILS), Faculty of Science (FNWI), University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands
⨯

Caenorhabditis elegans as a Model System for Studying Drug Induced Mitochondrial Toxicity

Richard de Boer,
Ruben L. Smith,
Winnok H. De Vos,
Erik M. M. Manders,
Stanley Brul,
Hans van der Spek

Published: May 13, 2015
https://doi.org/10.1371/journal.pone.0126220

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Mitochondria
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Mitochondrial DNA
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Caenorhabditis elegans
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Toxicity
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