Analysis of a Panel of 48 Cytokines in BAL Fluids Specifically Identifies IL-8 Levels as the Only Cytokine that Distinguishes Controlled Asthma from Uncontrolled Asthma, and Correlates Inversely with FEV1

Koa Hosoki; Sun Ying; Christopher Corrigan; Huibin Qi; Alexander Kurosky; Kristofer Jennings; Qian Sun; Istvan Boldogh; Sanjiv Sur

doi:10.1371/journal.pone.0126035

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Research Article

Analysis of a Panel of 48 Cytokines in BAL Fluids Specifically Identifies IL-8 Levels as the Only Cytokine that Distinguishes Controlled Asthma from Uncontrolled Asthma, and Correlates Inversely with FEV₁

Koa Hosoki ,

Contributed equally to this work with: Koa Hosoki, Sun Ying, Christopher Corrigan

Affiliation Department of Internal Medicine, Division of Allergy and Immunology, University of Texas Medical Branch, Galveston, Texas 77555, United States of America
⨯
Sun Ying ,

Contributed equally to this work with: Koa Hosoki, Sun Ying, Christopher Corrigan

Affiliation Division of Asthma, Allergy & Lung Biolog and MRC & Asthma UK Centre in Allergic Mechanisms of Asthma at King's College London, London, SE1, 9RT, United Kingdom
⨯
Christopher Corrigan ,

Contributed equally to this work with: Koa Hosoki, Sun Ying, Christopher Corrigan

Affiliation Division of Asthma, Allergy & Lung Biolog and MRC & Asthma UK Centre in Allergic Mechanisms of Asthma at King's College London, London, SE1, 9RT, United Kingdom
⨯
Huibin Qi,

Affiliation Department of Internal Medicine, Division of Allergy and Immunology, University of Texas Medical Branch, Galveston, Texas 77555, United States of America
⨯
Alexander Kurosky,

Affiliation Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77555, United States of America
⨯
Kristofer Jennings,

Affiliation Office of Biostatistics, Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, Texas 77555, United States of America
⨯
Qian Sun,

Affiliation Department of Internal Medicine, Division of Allergy and Immunology, University of Texas Medical Branch, Galveston, Texas 77555, United States of America
⨯
Istvan Boldogh,

Affiliation Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas 77555, United States of America
⨯
Sanjiv Sur

* E-mail: sasur@UTMB.EDU

Affiliation Department of Internal Medicine, Division of Allergy and Immunology, University of Texas Medical Branch, Galveston, Texas 77555, United States of America
⨯

Analysis of a Panel of 48 Cytokines in BAL Fluids Specifically Identifies IL-8 Levels as the Only Cytokine that Distinguishes Controlled Asthma from Uncontrolled Asthma, and Correlates Inversely with FEV₁

Koa Hosoki,
Sun Ying,
Christopher Corrigan,
Huibin Qi,
Alexander Kurosky,
Kristofer Jennings,
Qian Sun,
Istvan Boldogh,
Sanjiv Sur

Published: May 26, 2015
https://doi.org/10.1371/journal.pone.0126035

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