Incorporation of Porcine Adenovirus 4 Fiber Protein Enhances Infectivity of Adenovirus Vector on Dendritic Cells: Implications for Immune-Mediated Cancer Therapy

Ivy Wilkinson-Ryan; Julius Kim; Sojung Kim; Ferhat Ak; Lindzy Dodson; Marco Colonna; Matthew Powell; David Mutch; Dirk Spitzer; Ted Hansen; Simon P. Goedegebuure; David Curiel; William Hawkins

doi:10.1371/journal.pone.0125851

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Open Access

Peer-reviewed

Research Article

Incorporation of Porcine Adenovirus 4 Fiber Protein Enhances Infectivity of Adenovirus Vector on Dendritic Cells: Implications for Immune-Mediated Cancer Therapy

Ivy Wilkinson-Ryan,

Affiliation Washington University School of Medicine, Division of Gynecologic Oncology, St. Louis, United States of America
⨯
Julius Kim,

Affiliation University of Chicago, Department of Neuro-oncology, Chicago, United States of America
⨯
Sojung Kim,

Affiliation Washington University School of Medicine, Department of Pathology and Immunology, St. Louis, United States of America
⨯
Ferhat Ak,

Affiliation Saint Jans Gathuis Hospital, Department of SJG Apotheek, Weert, The Netherlands
⨯
Lindzy Dodson,

Affiliation Saint Louis University, Department of Biology, St. Louis, United States of America
⨯
Marco Colonna,

Affiliation Washington University School of Medicine, Department of Pathology and Immunology, St. Louis, United States of America
⨯
Matthew Powell,

Affiliation Washington University School of Medicine, Division of Gynecologic Oncology, St. Louis, United States of America
⨯
David Mutch,

Affiliation Washington University School of Medicine, Division of Gynecologic Oncology, St. Louis, United States of America
⨯
Dirk Spitzer,

Affiliation Washington University School of Medicine, Division of Surgery, St. Louis, United States of America
⨯
Ted Hansen,

Affiliation Washington University School of Medicine, Department of Pathology and Immunology, St. Louis, United States of America
⨯
Simon P. Goedegebuure,

Affiliation Washington University School of Medicine, Division of Surgery, St. Louis, United States of America
⨯
David Curiel,

Affiliation Washington University School of Medicine, Division of Cancer Biology, St. Louis, United States of America
⨯
William Hawkins

* E-mail: hawkinsw@wudosis.wustl.edu

Affiliation Washington University School of Medicine, Division of Surgery, St. Louis, United States of America
⨯

Incorporation of Porcine Adenovirus 4 Fiber Protein Enhances Infectivity of Adenovirus Vector on Dendritic Cells: Implications for Immune-Mediated Cancer Therapy

Ivy Wilkinson-Ryan,
Julius Kim,
Sojung Kim,
Ferhat Ak,
Lindzy Dodson,
Marco Colonna,
Matthew Powell,
David Mutch,
Dirk Spitzer,
Ted Hansen

Published: May 1, 2015
https://doi.org/10.1371/journal.pone.0125851

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