Predicting Human Genetic Interactions from Cancer Genome Evolution

Open Access

Peer-reviewed

Research Article

Xiaowen Lu,

Affiliation Department of Bioinformatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands
⨯
Wout Megchelenbrink,

Affiliations Department of Bioinformatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands, Institute for Computing and Information Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands
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Richard A. Notebaart ,

Contributed equally to this work with: Richard A. Notebaart, Martijn A. Huynen

* E-mail: Richard.Notebaart@radboudumc.nl (RAN); Martijn.Huijnen@radboudumc.nl (MAH)

Affiliations Department of Bioinformatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands, Centre for Systems Biology and Bioenergetics, Radboud University Medical Centre, Nijmegen, The Netherlands
⨯
Martijn A. Huynen

Contributed equally to this work with: Richard A. Notebaart, Martijn A. Huynen

* E-mail: Richard.Notebaart@radboudumc.nl (RAN); Martijn.Huijnen@radboudumc.nl (MAH)

Affiliations Department of Bioinformatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Centre, Nijmegen, The Netherlands, Centre for Systems Biology and Bioenergetics, Radboud University Medical Centre, Nijmegen, The Netherlands
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Cancers and neoplasms
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Cancer genomics
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Homozygosity
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Gene expression
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Human genomics
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Heterozygosity
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Malignant tumors
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Drug interactions
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