Positive Selection of Natural Poly-Reactive B Cells in the Periphery Occurs Independent of Heavy Chain Allelic Inclusion

Ying Xing; Qiuhe Ji; Ying Lin; Meng Fu; Jixin Gao; Ping Zhang; Xingbin Hu; Lei Feng; Yufeng Liu; Hua Han; Wei Li

doi:10.1371/journal.pone.0125747

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Open Access

Peer-reviewed

Research Article

Positive Selection of Natural Poly-Reactive B Cells in the Periphery Occurs Independent of Heavy Chain Allelic Inclusion

Ying Xing,

Affiliations Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi’an, China, Department of Endocrinology and Metabolism Disease, Xijing Hospital, Fourth Military Medical University, Xi’an, China, State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Xi’an, China
⨯
Qiuhe Ji,

Affiliation Department of Endocrinology and Metabolism Disease, Xijing Hospital, Fourth Military Medical University, Xi’an, China
⨯
Ying Lin,

Affiliation Department of Otolaryngology Head and Neck surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, China
⨯
Meng Fu,

Affiliation Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi’an, China
⨯
Jixin Gao,

Affiliation Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi’an, China
⨯
Ping Zhang,

Affiliation Department of Otolaryngology Head and Neck surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, China
⨯
Xingbin Hu,

Affiliation State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Xi’an, China
⨯
Lei Feng,

Affiliation State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Xi’an, China
⨯
Yufeng Liu,

Affiliation Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi’an, China
⨯
Hua Han ,

* E-mail: liwei1@fmmu.edu.cn (WL); huahan@fmmu.edu.cn (HH)

Affiliation State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, Fourth Military Medical University, Xi’an, China
⨯
Wei Li

* E-mail: liwei1@fmmu.edu.cn (WL); huahan@fmmu.edu.cn (HH)

Affiliation Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi’an, China
⨯

Positive Selection of Natural Poly-Reactive B Cells in the Periphery Occurs Independent of Heavy Chain Allelic Inclusion

Ying Xing,
Qiuhe Ji,
Ying Lin,
Meng Fu,
Jixin Gao,
Ping Zhang,
Xingbin Hu,
Lei Feng,
Yufeng Liu,
Hua Han

Published: May 19, 2015
https://doi.org/10.1371/journal.pone.0125747

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