Berberine Suppresses Adipocyte Differentiation via Decreasing CREB Transcriptional Activity

Juan Zhang; Hongju Tang; Ruyuan Deng; Ning Wang; Yuqing Zhang; Yao Wang; Yun Liu; Fengying Li; Xiao Wang; Libin Zhou

doi:10.1371/journal.pone.0125667

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Open Access

Peer-reviewed

Research Article

Berberine Suppresses Adipocyte Differentiation via Decreasing CREB Transcriptional Activity

Juan Zhang ,

Contributed equally to this work with: Juan Zhang, Hongju Tang

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Hongju Tang ,

Contributed equally to this work with: Juan Zhang, Hongju Tang

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Ruyuan Deng,

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Ning Wang,

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Yuqing Zhang,

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Yao Wang,

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Yun Liu,

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Fengying Li,

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Xiao Wang ,

* E-mail: wangxiao1976@hotmail.com (XW); libinzhou99@hotmail.com (LZ)

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯
Libin Zhou

* E-mail: wangxiao1976@hotmail.com (XW); libinzhou99@hotmail.com (LZ)

Affiliation Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
⨯

Berberine Suppresses Adipocyte Differentiation via Decreasing CREB Transcriptional Activity

Juan Zhang,
Hongju Tang,
Ruyuan Deng,
Ning Wang,
Yuqing Zhang,
Yao Wang,
Yun Liu,
Fengying Li,
Xiao Wang,
Libin Zhou

Published: April 30, 2015
https://doi.org/10.1371/journal.pone.0125667

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Adipocyte differentiation
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Phosphorylation
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