Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse

• Melissa A. Bates,

  Affiliations Department of Food Science and Human Nutrition, Michigan State University, East Lansing, Michigan, United States of America, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan, United States of America

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• Christina Brandenberger,

  Affiliations Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, United States of America, Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany

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• Ingeborg Langohr,

  Affiliation Department of Pathobiological Studies, School of Veterinary Medicine, Louisiana State University, Baton Rogue, Louisiana, United States of America

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• Kazuyoshi Kumagai,

  Affiliations Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan, United States of America, Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, United States of America

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• Jack R. Harkema,

  Affiliations Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan, United States of America, Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, Michigan, United States of America

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• Andrij Holian,

  Affiliation Center for Environmental Health Sciences, University of Montana, Missoula, Montana, United States of America

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• James J. Pestka

  * E-mail: pestka@msu.edu

  Affiliations Department of Food Science and Human Nutrition, Michigan State University, East Lansing, Michigan, United States of America, Center for Integrative Toxicology, Michigan State University, East Lansing, Michigan, United States of America

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