90Y-Labeled Anti-ROBO1 Monoclonal Antibody Exhibits Antitumor Activity against Small Cell Lung Cancer Xenografts

Kentaro Fujiwara; Keitaro Koyama; Kosuke Suga; Masako Ikemura; Yasutaka Saito; Akihiro Hino; Hiroko Iwanari; Osamu Kusano-Arai; Kenichi Mitsui; Hiroyuki Kasahara; Masashi Fukayama; Tatsuhiko Kodama; Takao Hamakubo; Toshimitsu Momose

doi:10.1371/journal.pone.0125468

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Open Access

Peer-reviewed

Research Article

⁹⁰Y-Labeled Anti-ROBO1 Monoclonal Antibody Exhibits Antitumor Activity against Small Cell Lung Cancer Xenografts

Kentaro Fujiwara,

Affiliation Department of Radiology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan
⨯
Keitaro Koyama,

Affiliation Department of Radiology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan
⨯
Kosuke Suga,

Affiliation SANKYO LABO SERVICE Co., Ltd., Edogawaku, Tokyo, Japan
⨯
Masako Ikemura,

Affiliation Department of Pathology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan
⨯
Yasutaka Saito,

Affiliation FUJIFILM RI Pharma Co., Ltd., SAMMU-CITY, CHIBA, Japan
⨯
Akihiro Hino,

Affiliation FUJIFILM RI Pharma Co., Ltd., SAMMU-CITY, CHIBA, Japan
⨯
Hiroko Iwanari,

Affiliation Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo, Japan
⨯
Osamu Kusano-Arai,

Affiliation Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo, Japan
⨯
Kenichi Mitsui,

Affiliation Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo, Japan
⨯
Hiroyuki Kasahara,

Affiliation FUJIFILM RI Pharma Co., Ltd., SAMMU-CITY, CHIBA, Japan
⨯
Masashi Fukayama,

Affiliation Department of Pathology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan
⨯
Tatsuhiko Kodama,

Affiliation Department of Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo, Japan
⨯
Takao Hamakubo,

Affiliation Department of Quantitative Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Meguro-ku, Tokyo, Japan
⨯
Toshimitsu Momose

* E-mail: tmomo-tky@umin.ac.jp

Affiliation Department of Radiology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan
⨯

⁹⁰Y-Labeled Anti-ROBO1 Monoclonal Antibody Exhibits Antitumor Activity against Small Cell Lung Cancer Xenografts

Kentaro Fujiwara,
Keitaro Koyama,
Kosuke Suga,
Masako Ikemura,
Yasutaka Saito,
Akihiro Hino,
Hiroko Iwanari,
Osamu Kusano-Arai,
Kenichi Mitsui,
Hiroyuki Kasahara

Published: May 27, 2015
https://doi.org/10.1371/journal.pone.0125468

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