Sequential FOLFIRI.3 + Gemcitabine Improves Health-Related Quality of Life Deterioration-Free Survival of Patients with Metastatic Pancreatic Adenocarcinoma: A Randomized Phase II Trial

Amélie Anota; Guillaume Mouillet; Isabelle Trouilloud; Anne-Claire Dupont-Gossart; Pascal Artru; Thierry Lecomte; Aziz Zaanan; Mélanie Gauthier; Francine Fein; Olivier Dubreuil; Sophie Paget-Bailly; Julien Taieb; Franck Bonnetain

doi:10.1371/journal.pone.0125350

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Open Access

Peer-reviewed

Research Article

Sequential FOLFIRI.3 + Gemcitabine Improves Health-Related Quality of Life Deterioration-Free Survival of Patients with Metastatic Pancreatic Adenocarcinoma: A Randomized Phase II Trial

Amélie Anota ,

* E-mail: aanota@chu-besancon.fr

Affiliations National Quality of Life in Oncology Platform, Besançon, France, Methodological and Quality of Life in Oncology Unit (EA 3181), University Hospital of Besançon, Besançon, France
⨯
Guillaume Mouillet,

Affiliation Methodological and Quality of Life in Oncology Unit (EA 3181), University Hospital of Besançon, Besançon, France
⨯
Isabelle Trouilloud,

Affiliation Department of Gastroenterology and Digestive Oncology, Georges Pompidou European Hospital, University of Paris Descartes, Paris, France
⨯
Anne-Claire Dupont-Gossart,

Affiliation Department of Gastroenterology, University Hospital of Besançon, Besançon, France
⨯
Pascal Artru,

Affiliation Hepato-Gastro-Enterology and Digestive Oncology Department, Hospital Jean Mermoz, Lyon, France
⨯
Thierry Lecomte,

Affiliation Department of Gastroenterology and Digestive Oncology, University Hospital of Tours- Trousseau Hospital, Chambray-Les-Tours, France
⨯
Aziz Zaanan,

Affiliation Department of Gastroenterology and Digestive Oncology, Georges Pompidou European Hospital, University of Paris Descartes, Paris, France
⨯
Mélanie Gauthier,

Affiliation Biostatistics and Quality of Life Unit, Centre Georges François Leclerc, Dijon, France
⨯
Francine Fein,

Affiliation Department of Gastroenterology, University Hospital of Besançon, Besançon, France
⨯
Olivier Dubreuil,

Affiliation Department of Gastroenterology and Digestive Oncology, Georges Pompidou European Hospital, University of Paris Descartes, Paris, France
⨯
Sophie Paget-Bailly,

Affiliation Methodological and Quality of Life in Oncology Unit (EA 3181), University Hospital of Besançon, Besançon, France
⨯
Julien Taieb,

Affiliation Department of Gastroenterology and Digestive Oncology, Georges Pompidou European Hospital, University of Paris Descartes, Paris, France
⨯
Franck Bonnetain

Affiliations National Quality of Life in Oncology Platform, Besançon, France, Methodological and Quality of Life in Oncology Unit (EA 3181), University Hospital of Besançon, Besançon, France
⨯

Sequential FOLFIRI.3 + Gemcitabine Improves Health-Related Quality of Life Deterioration-Free Survival of Patients with Metastatic Pancreatic Adenocarcinoma: A Randomized Phase II Trial

Amélie Anota,
Guillaume Mouillet,
Isabelle Trouilloud,
Anne-Claire Dupont-Gossart,
Pascal Artru,
Thierry Lecomte,
Aziz Zaanan,
Mélanie Gauthier,
Francine Fein,
Olivier Dubreuil

Published: May 26, 2015
https://doi.org/10.1371/journal.pone.0125350

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