Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer’s-Associated Aβ Oligomers

• Kyle C. Wilcox,

  Affiliation Department of Neurobiology, Northwestern University, Evanston, IL, United States of America

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• Matthew R. Marunde,

  Affiliation Department of Neurobiology, Northwestern University, Evanston, IL, United States of America

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• Aditi Das,

  Affiliations Department of Comparative Biosciences, University of Illinois—Urbana Champaign, Urbana, IL, United States of America, Department of Biochemistry, University of Illinois—Urbana Champaign, Urbana, IL, United States of America

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• Pauline T. Velasco,

  Affiliation Department of Neurobiology, Northwestern University, Evanston, IL, United States of America

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• Benjamin D. Kuhns,

  Affiliation Department of Neurobiology, Northwestern University, Evanston, IL, United States of America

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• Michael T. Marty,

  Affiliation Department of Chemistry, University of Illinois—Urbana Champaign, Urbana, IL, United States of America

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• Haoming Jiang,

  Affiliation Department of Neurobiology, Northwestern University, Evanston, IL, United States of America

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• Chi-Hao Luan,

  Affiliation High Throughput Analysis Laboratory and Department of Molecular Biosciences, Northwestern University, Evanston, IL, United States of America

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• Stephen G. Sligar,

  Affiliations Department of Biochemistry, University of Illinois—Urbana Champaign, Urbana, IL, United States of America, Department of Chemistry, University of Illinois—Urbana Champaign, Urbana, IL, United States of America

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• William L. Klein

  * E-mail: wklein@northwestern.edu

  Affiliation Department of Neurobiology, Northwestern University, Evanston, IL, United States of America

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