Altered Activation of Innate Immunity Associates with White Matter Volume and Diffusion in First-Episode Psychosis

• Teemu Mäntylä ,

  Contributed equally to this work with: Teemu Mäntylä, Outi Mantere

  Affiliations Mental Health Unit, National Institute for Health and Welfare, Helsinki, Finland, Brain Research Unit, O.V. Lounasmaa Laboratory and Advanced Magnetic Imaging Centre, Aalto NeuroImaging, Aalto University School of Science, Espoo, Finland, Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland

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• Outi Mantere ,

  Contributed equally to this work with: Teemu Mäntylä, Outi Mantere

  Affiliations Mental Health Unit, National Institute for Health and Welfare, Helsinki, Finland, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland, Institute of Clinical Medicine, Department of Psychiatry, Helsinki University, Helsinki, Finland

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• Tuukka T. Raij,

  Affiliations Brain Research Unit, O.V. Lounasmaa Laboratory and Advanced Magnetic Imaging Centre, Aalto NeuroImaging, Aalto University School of Science, Espoo, Finland, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland

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• Tuula Kieseppä,

  Affiliations Mental Health Unit, National Institute for Health and Welfare, Helsinki, Finland, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland

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• Hanna Laitinen,

  Affiliation Vaccination Programme Unit, National Institute for Health and Welfare, Helsinki, Finland

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• Jaana Leiviskä,

  Affiliation Genomics and Biomarkers Unit, National Institute for Health and Welfare, Helsinki, Finland

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• Minna Torniainen,

  Affiliations Mental Health Unit, National Institute for Health and Welfare, Helsinki, Finland, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

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• Lauri Tuominen,

  Affiliations Turku PET centre, University of Turku, Turku, Finland, Department of Psychiatry, University of Turku, Turku, Finland

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• Outi Vaarala,

  Affiliations Respiratory, Inflammatory and Autoimmunity, Innovative Medicine, AstraZeneca R & D, Mölndal, Sweden, Institute of Clinical Medicine, University of Helsinki, Helsinki, Finland

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• Jaana Suvisaari

  * E-mail: jaana.suvisaari@thl.fi

  Affiliation Mental Health Unit, National Institute for Health and Welfare, Helsinki, Finland

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