First-In-Human, Double-Blind, Placebo-Controlled, Randomized, Dose-Escalation Study of BG00010, a Glial Cell Line-Derived Neurotrophic Factor Family Member, in Subjects with Unilateral Sciatica

Open Access

Peer-reviewed

Research Article

Paul E. Rolan ,

* E-mail: paul.rolan@adelaide.edu.au

Affiliations Clinical Pharmacology, School of Medical Sciences, University of Adelaide, Adelaide, Australia, Pain and Anaesthesia Research Clinic, Royal Adelaide Hospital, Adelaide, Australia, Pain Management Unit, Royal Adelaide Hospital, Adelaide, Australia
⨯
Gilmore O’Neill,

Affiliation Biogen IDEC, Cambridge, MA, United States of America
⨯
Eve Versage,

Affiliation Biogen IDEC, Cambridge, MA, United States of America
⨯
Jitesh Rana,

Affiliation Biogen IDEC, Cambridge, MA, United States of America
⨯
Yongqiang Tang,

Affiliation Biogen IDEC, Cambridge, MA, United States of America
⨯
Gerald Galluppi,

Affiliation Biogen IDEC, Cambridge, MA, United States of America
⨯
Ernesto Aycardi

Affiliation Biogen IDEC, Cambridge, MA, United States of America
⨯

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Adjustment of dosage at steady state
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