Chloroform-Methanol Residue of Coxiella burnetii Markedly Potentiated the Specific Immunoprotection Elicited by a Recombinant Protein Fragment rOmpB-4 Derived from Outer Membrane Protein B of Rickettsia rickettsii in C3H/HeN Mice

Open Access

Peer-reviewed

Research Article

Wenping Gong,

Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing, China
⨯
Pengcheng Wang,

Affiliations State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing, China, Department of Clinical Laboratory, the 105th Hospital of PLA, Hefei, Anhui, China
⨯
Xiaolu Xiong ,

* E-mail: wenbohai@yahoo.com (BW); xiongxiaolu624@sohu.com (XX)

Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing, China
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Jun Jiao,

Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing, China
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Xiaomei Yang,

Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing, China
⨯
Bohai Wen

* E-mail: wenbohai@yahoo.com (BW); xiongxiaolu624@sohu.com (XX)

Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing, China
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Coxiella burnetii
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Rickettsia rickettsii
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Spleen
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Enzyme-linked immunoassays
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Antibodies
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Macrophages
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Q fever
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Respiratory infections
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