Enhanced IMP3 Expression Activates NF-кB Pathway and Promotes Renal Cell Carcinoma Progression

Xuelian Pei; Muhan Li; Jun Zhan; Yu Yu; Xiaofan Wei; Lizhao Guan; Hakan Aydin; Paul Elson; Ming Zhou; Huiying He; Hongquan Zhang

doi:10.1371/journal.pone.0124338

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Open Access

Peer-reviewed

Research Article

Enhanced IMP3 Expression Activates NF-кB Pathway and Promotes Renal Cell Carcinoma Progression

Xuelian Pei,

Affiliations Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, PR China, Department of Anatomy, Histology and Embryology, Peking University Health Science Center, Beijing, PR China, Department of Histology and Embryology and Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University School of Medicine, Shihezi, Xinjiang, PR China
⨯
Muhan Li,

Affiliations Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, PR China, Department of Pathology, Peking University Health Science Center, Beijing, PR China
⨯
Jun Zhan,

Affiliations Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, PR China, Department of Anatomy, Histology and Embryology, Peking University Health Science Center, Beijing, PR China
⨯
Yu Yu,

Affiliations Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, PR China, Department of Anatomy, Histology and Embryology, Peking University Health Science Center, Beijing, PR China
⨯
Xiaofan Wei,

Affiliations Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, PR China, Department of Anatomy, Histology and Embryology, Peking University Health Science Center, Beijing, PR China
⨯
Lizhao Guan,

Affiliations Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, PR China, Department of Anatomy, Histology and Embryology, Peking University Health Science Center, Beijing, PR China
⨯
Hakan Aydin,

Affiliation Institute of Pathology and Laboratory Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio, United States of America
⨯
Paul Elson,

Affiliation Department of Quantitative Health Sciences, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio, United States of America
⨯
Ming Zhou,

Affiliation Institute of Pathology and Laboratory Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, Ohio, United States of America
⨯
Huiying He ,

* E-mail: huiyinghe@bjmu.edu.cn (HH); Hongquan.Zhang@bjmu.edu.cn (HZ)

Affiliations Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, PR China, Department of Pathology, Peking University Health Science Center, Beijing, PR China
⨯
Hongquan Zhang

* E-mail: huiyinghe@bjmu.edu.cn (HH); Hongquan.Zhang@bjmu.edu.cn (HZ)

Affiliations Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, PR China, Department of Anatomy, Histology and Embryology, Peking University Health Science Center, Beijing, PR China
⨯

Enhanced IMP3 Expression Activates NF-кB Pathway and Promotes Renal Cell Carcinoma Progression

Xuelian Pei,
Muhan Li,
Jun Zhan,
Yu Yu,
Xiaofan Wei,
Lizhao Guan,
Hakan Aydin,
Paul Elson,
Ming Zhou,
Huiying He

Published: April 28, 2015
https://doi.org/10.1371/journal.pone.0124338

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