The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation

Shota Yamana; Amina Tokiyama; Kiyohito Mizutani; Ken-ichi Hirata; Yoshimi Takai; Yoshiyuki Rikitake

doi:10.1371/journal.pone.0124259

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Peer-reviewed

Research Article

The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation

Shota Yamana,

Affiliation Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
⨯
Amina Tokiyama,

Affiliation Division of Signal Transduction, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
⨯
Kiyohito Mizutani,

Affiliations Division of Molecular and Cellular Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, Division of Pathogenetic Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
⨯
Ken-ichi Hirata,

Affiliation Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
⨯
Yoshimi Takai,

Affiliations Division of Molecular and Cellular Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, Division of Pathogenetic Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
⨯
Yoshiyuki Rikitake

* E-mail: rikitake@med.kobe-u.ac.jp

Affiliations Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, Division of Signal Transduction, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, Division of Molecular and Cellular Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
⨯

The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation

Shota Yamana,
Amina Tokiyama,
Kiyohito Mizutani,
Ken-ichi Hirata,
Yoshimi Takai,
Yoshiyuki Rikitake

Published: April 20, 2015
https://doi.org/10.1371/journal.pone.0124259

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Cell movement
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Signal inhibition
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Cadherins
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