Liver Injury and Fibrosis Induced by Dietary Challenge in the Ossabaw Miniature Swine

Tiebing Liang; Mouhamad Alloosh; Lauren N. Bell; Allison Fullenkamp; Romil Saxena; William Van Alstine; Phelan Bybee; Klára Werling; Michael Sturek; Naga Chalasani; Howard C. Masuoka

doi:10.1371/journal.pone.0124173

Loading metrics

Open Access

Peer-reviewed

Research Article

Liver Injury and Fibrosis Induced by Dietary Challenge in the Ossabaw Miniature Swine

Tiebing Liang,

Affiliation Department of Medicine, Division of Gastroenterology/Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Mouhamad Alloosh,

Affiliation Department of Cellular & Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Lauren N. Bell,

Affiliation Department of Medicine, Division of Gastroenterology/Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Allison Fullenkamp,

Affiliation Department of Medicine, Division of Gastroenterology/Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Romil Saxena,

Affiliation Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
William Van Alstine,

Affiliation School of Veterinary Medicine, Purdue University, Lafayette, Indiana, United States of America
⨯
Phelan Bybee,

Affiliation School of Biomedical Engineering, Purdue University, Lafayette, Indiana, United States of America
⨯
Klára Werling,

Affiliation 2nd Department of Medicine, Semmelweis University, Budapest, Hungary
⨯
Michael Sturek,

Affiliation Department of Cellular & Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Naga Chalasani,

Affiliations Department of Medicine, Division of Gastroenterology/Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Cellular & Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Howard C. Masuoka

* E-mail: hmasuoka@iu.edu

Current address: Department of Medicine, Division of Gastroenterology and Hepatology, Indiana University School of Medicine, 702 Rotary Circle, Indianapolis, Indiana, 46202, United States of America

Affiliations Department of Medicine, Division of Gastroenterology/Hepatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Cellular & Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯

Liver Injury and Fibrosis Induced by Dietary Challenge in the Ossabaw Miniature Swine

Tiebing Liang,
Mouhamad Alloosh,
Lauren N. Bell,
Allison Fullenkamp,
Romil Saxena,
William Van Alstine,
Phelan Bybee,
Klára Werling,
Michael Sturek,
Naga Chalasani

Published: May 15, 2015
https://doi.org/10.1371/journal.pone.0124173

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Diet
Is the Subject Area "Diet" applicable to this article?

Thanks for your feedback.
Swine
Is the Subject Area "Swine" applicable to this article?

Thanks for your feedback.
Cholesterol
Is the Subject Area "Cholesterol" applicable to this article?

Thanks for your feedback.
Hepatocytes
Is the Subject Area "Hepatocytes" applicable to this article?

Thanks for your feedback.
Fatty liver
Is the Subject Area "Fatty liver" applicable to this article?

Thanks for your feedback.
Fibrosis
Is the Subject Area "Fibrosis" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Nonalcoholic steatohepatitis
Is the Subject Area "Nonalcoholic steatohepatitis" applicable to this article?

Thanks for your feedback.