Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats

Tingting Wang; Li Zhao; Yunliang Guo; Meizeng Zhang; Haitao Pei

doi:10.1371/journal.pone.0124099

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Peer-reviewed

Research Article

Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats

Tingting Wang,

Affiliation Institute of Cerebrovascular Diseases, Affiliated Hospital of Qingdao University, Shandong Provincial Collaborative Innovation Center for Neurodegenerative Disorders; Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province, Qingdao, 266003, P. R. China
⨯
Li Zhao,

Affiliation Institute of Cerebrovascular Diseases, Affiliated Hospital of Qingdao University, Shandong Provincial Collaborative Innovation Center for Neurodegenerative Disorders; Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province, Qingdao, 266003, P. R. China
⨯
Yunliang Guo ,

* E-mail: guoqdsd@163.com

Affiliation Institute of Cerebrovascular Diseases, Affiliated Hospital of Qingdao University, Shandong Provincial Collaborative Innovation Center for Neurodegenerative Disorders; Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province, Qingdao, 266003, P. R. China
⨯
Meizeng Zhang,

Affiliation Institute of Cerebrovascular Diseases, Affiliated Hospital of Qingdao University, Shandong Provincial Collaborative Innovation Center for Neurodegenerative Disorders; Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province, Qingdao, 266003, P. R. China
⨯
Haitao Pei

Affiliation Institute of Cerebrovascular Diseases, Affiliated Hospital of Qingdao University, Shandong Provincial Collaborative Innovation Center for Neurodegenerative Disorders; Taishan Scholars Construction Project Excellent Innovative Team of Shandong Province, Qingdao, 266003, P. R. China
⨯

Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats

Tingting Wang,
Li Zhao,
Yunliang Guo,
Meizeng Zhang,
Haitao Pei

Published: April 30, 2015
https://doi.org/10.1371/journal.pone.0124099

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Apoptosis
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Cerebral ischemia
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Neurons
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Brain damage
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Blood-brain barrier
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Neuronal morphology
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Basement membrane
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Ears
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