Iron-Hepcidin Dysmetabolism, Anemia and Renal Hypoxia, Inflammation and Fibrosis in the Remnant Kidney Rat Model

Patrícia Garrido; Sandra Ribeiro; João Fernandes; Helena Vala; Elsa Bronze-da-Rocha; Petronila Rocha-Pereira; Luís Belo; Elísio Costa; Alice Santos-Silva; Flávio Reis

doi:10.1371/journal.pone.0124048

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Open Access

Peer-reviewed

Research Article

Iron-Hepcidin Dysmetabolism, Anemia and Renal Hypoxia, Inflammation and Fibrosis in the Remnant Kidney Rat Model

Patrícia Garrido,

Affiliations Laboratory of Pharmacology & Experimental Therapeutics, Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal, Center for Neuroscience and Cell Biology—Institute for Biomedical Imaging and Life Sciences (CNC.IBILI) Research Unit, University of Coimbra, Coimbra, Portugal
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Sandra Ribeiro,

Affiliation Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal
⨯
João Fernandes,

Affiliations Laboratory of Pharmacology & Experimental Therapeutics, Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal, Center for Neuroscience and Cell Biology—Institute for Biomedical Imaging and Life Sciences (CNC.IBILI) Research Unit, University of Coimbra, Coimbra, Portugal
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Helena Vala,

Affiliation Center for Studies in Education, Technologies and Health (CI&DETS), Agrarian School of Viseu, Polytechnic Institute of Viseu, Viseu, Portugal
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Elsa Bronze-da-Rocha,

Affiliation Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal
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Petronila Rocha-Pereira,

Affiliation Research Centre in Health Sciences, University of Beira Interior, Covilhã, Portugal
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Luís Belo,

Affiliation Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal
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Elísio Costa,

Affiliation Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal
⨯
Alice Santos-Silva,

Affiliation Research Unit on Applied Molecular Biosciences (UCIBIO), REQUIMTE, Department of Biological Sciences, Laboratory of Biochemistry, Faculty of Pharmacy, University of Porto, Porto, Portugal
⨯
Flávio Reis

* E-mail: freis@fmed.uc.pt

Affiliations Laboratory of Pharmacology & Experimental Therapeutics, Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal, Center for Neuroscience and Cell Biology—Institute for Biomedical Imaging and Life Sciences (CNC.IBILI) Research Unit, University of Coimbra, Coimbra, Portugal
⨯

Iron-Hepcidin Dysmetabolism, Anemia and Renal Hypoxia, Inflammation and Fibrosis in the Remnant Kidney Rat Model

Patrícia Garrido,
Sandra Ribeiro,
João Fernandes,
Helena Vala,
Elsa Bronze-da-Rocha,
Petronila Rocha-Pereira,
Luís Belo,
Elísio Costa,
Alice Santos-Silva,
Flávio Reis

Published: April 13, 2015
https://doi.org/10.1371/journal.pone.0124048

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