Exogenous Restoration of TUSC2 Expression Induces Responsiveness to Erlotinib in Wildtype Epidermal Growth Factor Receptor (EGFR) Lung Cancer Cells through Context Specific Pathways Resulting in Enhanced Therapeutic Efficacy

• Bingbing Dai ,

  Contributed equally to this work with: Bingbing Dai, Shaoyu Yan

  Affiliation Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America

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• Shaoyu Yan ,

  Contributed equally to this work with: Bingbing Dai, Shaoyu Yan

  Affiliation Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America

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• Humberto Lara-Guerra,

  Affiliation Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America

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• Hiroyuki Kawashima,

  Affiliations Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America, Nigata University Graduate School of Medical and Dental Sciences, Nigata, Japan

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• Ryo Sakai,

  Affiliations Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America, Okayama Citizens’ Hospital, Okayama, Japan

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• Gitanjali Jayachandran,

  Affiliation Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America

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• Mourad Majidi,

  Affiliation Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America

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• Reza Mehran,

  Affiliation Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America

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• Jing Wang,

  Affiliation Department of Bioinfomatics and Computational Biology, UT MD Anderson Cancer Center, Houston, Texas, United States of America

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• B. Nebiyou Bekele,

  Affiliations Department of Biostatistics, UT MD Anderson Cancer Center, Houston, Texas, United States of America, Gilead Sciences, Foster City, California, United States of America

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• Veerabhadran Baladandayuthapani,

  Affiliation Department of Biostatistics, UT MD Anderson Cancer Center, Houston, Texas, United States of America

  ⨯
• Suk-Young Yoo,

  Affiliation Department of Bioinfomatics and Computational Biology, UT MD Anderson Cancer Center, Houston, Texas, United States of America

  ⨯
• Ying Wang,

  Affiliation Department of Bioinfomatics and Computational Biology, UT MD Anderson Cancer Center, Houston, Texas, United States of America

  ⨯
• Jun Ying,

  Affiliation Department of Biostatistics, UT MD Anderson Cancer Center, Houston, Texas, United States of America

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• Feng Meng,

  Affiliation Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America

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• Lin Ji,

  Affiliation Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America

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•  [ ... ],
• Jack A. Roth

  * E-mail: jroth@mdanderson.org

  Affiliation Section of Thoracic Molecular Oncology, Department of Thoracic and Cardiovascular Surgery, University of Texas (UT) MD Anderson Cancer Center, Houston, Texas, United States of America

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