Characterization of the Loss of SUMO Pathway Function on Cancer Cells and Tumor Proliferation

Open Access

Peer-reviewed

Research Article

Xingyue He ,

* E-mail: xingyue.he@takeda.com (XH); nbence@nurix-inc.com (NB)

Affiliation Oncology Drug Discovery Unit, Takeda Pharmaceuticals International Co., Cambridge, United States of America
⨯
Jessica Riceberg,

Affiliation Oncology Drug Discovery Unit, Takeda Pharmaceuticals International Co., Cambridge, United States of America
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Sai M. Pulukuri,

Affiliation Oncology Drug Discovery Unit, Takeda Pharmaceuticals International Co., Cambridge, United States of America
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Steve Grossman,

Affiliation Oncology Drug Discovery Unit, Takeda Pharmaceuticals International Co., Cambridge, United States of America
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Vaishali Shinde,

Affiliation Oncology Drug Discovery Unit, Takeda Pharmaceuticals International Co., Cambridge, United States of America
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Pooja Shah,

Affiliation Oncology Drug Discovery Unit, Takeda Pharmaceuticals International Co., Cambridge, United States of America
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James E. Brownell,

Affiliation Oncology Drug Discovery Unit, Takeda Pharmaceuticals International Co., Cambridge, United States of America
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Larry Dick,

Affiliation Oncology Drug Discovery Unit, Takeda Pharmaceuticals International Co., Cambridge, United States of America
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John Newcomb,

Affiliation Oncology Drug Discovery Unit, Takeda Pharmaceuticals International Co., Cambridge, United States of America
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Neil Bence

* E-mail: xingyue.he@takeda.com (XH); nbence@nurix-inc.com (NB)

Affiliation Nurix, Inc. San Francisco, United States of America
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SUMOylation
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Breast cancer
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Malignant tumors
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Apoptosis
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Cancers and neoplasms
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Cell staining
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Cancer treatment
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Nuclear bodies
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