Closed-Loop Control Better than Open-Loop Control of Profofol TCI Guided by BIS: A Randomized, Controlled, Multicenter Clinical Trial to Evaluate the CONCERT-CL Closed-Loop System

Yu Liu; Min Li; Dong Yang; Xuena Zhang; Anshi Wu; Shanglong Yao; Zhanggang Xue; Yun Yue

doi:10.1371/journal.pone.0123862

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Peer-reviewed

Research Article

Closed-Loop Control Better than Open-Loop Control of Profofol TCI Guided by BIS: A Randomized, Controlled, Multicenter Clinical Trial to Evaluate the CONCERT-CL Closed-Loop System

Yu Liu ,

Contributed equally to this work with: Yu Liu, Min Li, Dong Yang

Affiliation Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China
⨯
Min Li ,

Contributed equally to this work with: Yu Liu, Min Li, Dong Yang

Affiliation Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China
⨯
Dong Yang ,

Contributed equally to this work with: Yu Liu, Min Li, Dong Yang

Affiliation Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China
⨯
Xuena Zhang,

Affiliation Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China
⨯
Anshi Wu,

Affiliation Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China
⨯
Shanglong Yao ,

¶‡These authors share equal senior authorship.

Affiliation Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China
⨯
Zhanggang Xue ,

¶‡These authors share equal senior authorship.

Affiliation Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China
⨯
Yun Yue

* E-mail: yueyun@hotmail.com

¶‡These authors share equal senior authorship.

Affiliation Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of China
⨯

Closed-Loop Control Better than Open-Loop Control of Profofol TCI Guided by BIS: A Randomized, Controlled, Multicenter Clinical Trial to Evaluate the CONCERT-CL Closed-Loop System

Yu Liu,
Min Li,
Dong Yang,
Xuena Zhang,
Anshi Wu,
Shanglong Yao,
Zhanggang Xue,
Yun Yue

Published: April 17, 2015
https://doi.org/10.1371/journal.pone.0123862

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